Table 2.

Two-way ANOVA table

Figure	Factor	F (DFn, DFd)	p value	Multiple comparisons
A	Time	F(1.702,48.23) = 1085	p < 0.0001	n/a
	Drug	F(2,30) = 6.958	p = 0.0033	1 h, vehicle vs AM6545 p = 0.0002, vehicle vs ATR p = 0.0455; 6 h, vehicle vs AM6545 p = 0.0002; 12 h, vehicle vs AM6545 p = 0.0025; 24 h, vehicle vs AM6545 p = 0.0008, vehicle vs ATR p = 0.0195
	Time × Drug	F(6,85) = 4.619	p = 0.0004	n/a
B	Time	F(1.292,56.85) = 616.7	p < 0.0001	n/a
	Drug	F(2,45) = 2.272	p = 0.1148	n/a
	Time × drug	F(6,132) = 2.082	p = 0.0595	n/a
C	Time	F(2.130,58.94) = 74.59	p < 0.0001	n/a
	Drug	F(2,29) = 2.217	p = 0.1271	n/a
	Time × drug	F(6,83) = 1.707	p = 0.1296	n/a
D	Time	F(1.849,80.75) = 68.67	p < 0.0001	n/a
	Drug	F(2,45) = 3.398	p = 0.0422	1 h, vehicle vs AM6545 p = 0.0493; 6 h, vehicle vs AM6545 p = 0.0081; 24 h, vehicle vs AM6545 p = 0.0230
	Time × drug	F(6,131) = 2.619	p = 0.0197	n/a