Table 1.
Demographics and clinical characteristics of all patients who received treatment for aneurysmal subarachnoid hemorrhage from 2016–2020.
| No Symptomatic Thromboembolic Complications (n=161) | Symptomatic Thromboembolic Complications (n=33) | p-value | |
|---|---|---|---|
| Age (mean years) (SD) | 56.0 (14.2) | 55.5 (13.3) | 0.84 |
| Gender | 0.04 | ||
| Female (%) | 119 (74) | 18 (55) | |
| Male (%) | 42 (26) | 15 (45) | |
| Race | 0.53 | ||
| White (%) | 70 (43) | 15 (45) | |
| Black (%) | 59 (37) | 15 (45) | |
| Hispanic (%) | 15 (10) | 2 (6) | |
| Other (%) | 15 (10) | 1 (3) | |
| BMI (mean) (SD) | 28.2 (6.9) | 26.5 (8.9) | 0.31 |
| Hunt Hess Score | <0.01 | ||
| 2 or less (%) | 87 (51) | 9 (27) | |
| >2 (%) | 74 (49) | 24 (73) | |
| Glasgow Coma Scale | <0.01 | ||
| >12 (%) | 114 (71) | 14 (42) | |
| 8 to 12 (%) | 17 (11) | 11 (33) | |
| <8 (%) | 30 (19) | 8 (24) | |
| IVH (%) | 103 (64) | 27 (82) | 0.07 |
| ICH (%) | 37 (23) | 14 (42) | 0.04 |
| Hydrocephalus requiring EVD (%) | 59 (37) | 25 (76) | <0.01 |
| Craniotomy (%) | 72 (45) | 18 (56) | 0.40 |
| Coiling (%) | 86 (53) | 15 (45) | 0.52 |
| Mechanical Ventilation (%) | 54 (34) | 22 (67) | <0.01 |
| Pre-operative anti-coagulant or anti-platelet use (%) | 27 (17) | 8 (24) | 0.44 |
| Received Platelet Infusion (%) | 34 (21) | 12 (36) | 0.10 |
| Number of aneurysms treated | 0.47 | ||
| 1 (%) | 130 (81) | 29 (88) | |
| >1 (%) | 31 (19) | 4 (12) | |
| Received ASA post-operatively (%) | 55 (34) | 7 (21) | 0.21 |
| New hemorrhage post-operatively (%) | 11 (7) | 6 (18) | 0.08 |
| Time to heparin administration from admission (median hours) (SD) | 52.0 (31.0) | 59.9 (24.4) | 0.80 |
| Heparin Dose Administered | 0.17 | ||
| 5000 U SQ every 12 hours (%) | 42 (26) | 8 (24) | |
| 5000 U SQ every 8 hours (%) | 115 (71) | 22 (67) | |
| Other (%) | 4 (2) | 3 (9) | |
| Delayed heparinization (%) | 72 (46) | 23 (70) | 0.02 |
BMI, body mass index; EVD, external ventricular drain; ICH, intracerebral hemorrhage; IVH, intraventricular hemorrhage; SD, standard deviation; SQ, subcutaneously
Bolded values indicate statistical significance (p<0.05)