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. 2024 May 1;15:1361840. doi: 10.3389/fendo.2024.1361840

Table 2.

Results of laboratory analyses at the before and the after monitoring of the study for two groups formed according to the annual percentage change in eGFR.

Group1
Annual percentage in eGFR>-5.48%/year
Group2
Annual percentage in eGFR≤-5.48%/year
Before After P value Before After P value
Annual percentage change in eGFR,%/year 0.33(5.9) -14.8(11.0)
Annual percentage change in serum TBIL,%/year 0.38(11.3) -8.25(14.7)
eGFR, ml/min/1.73m2 89.9(46.0) 96.6(44.4) 0.460 84.4(61.9) 38.1(37.3) <0.001
BUN, mmol/L 5.2(2.5) 6.4(3.1) 0.008 6.2(2.9) 10.4(9.0) <0.001
Scr, µmol/L 77.0(31.7) 71.5(30.5) 0.039 79.0(54.0) 147.0(152.0) <0.001
ACR,A2/A3 24/16 20/20 0.369 16/47 7/56 0.038
GLU, mmol/L 10.0(5.9) 10.2(5.7) 0.587 9.2(4.3) 7.7(4.3) 0.031
HbA1c, % 9.2(1.5) 8.7(3.0) 0.798 9.7(3.3) 8.2(2.5) <0.001
ALT, U/L 19.5(19.5) 18.5(13) 0.231 17.0(12.0) 14.0(8.2) <0.001
AST, U/L 19.0(14.9) 19.5(7.5) 0.214 18.0(7.5) 15.0(7.0) <0.001
GGT, U/L 28.0(26.5) 26.5(20.5) 0.261 25.0(20.3) 24.0(11.8) 0.084
serum TBIL, µmol/L 12.6(7.8) 13.8(7.0) 0.941 12.2(7.6) 8.7(4.6) <0.001
DBIL, µmol/L 3.4(2.1) 3.5(1.6) 0.411 2.8(1.9) 2.2(1.4) 0.010
IBIL, µmol/L 9.7(6.5) 9.7(6.4) 0.752 9.1(6.2) 6.4(2.9) <0.001

ACR, A2:<300mg/g; A3: ≥300mg/g.