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. Author manuscript; available in PMC: 2024 May 16.
Published in final edited form as: Toxicology. 2023 Nov 30;500:153692. doi: 10.1016/j.tox.2023.153692

Figure 11: Mechanisms of APAP-induced hepatic necrosis and renal apoptosis.

Figure 11:

(A) Schematic illustrations of mitochondria-induced cell necrosis in the liver after APAP overdose (B) ER stress-induced cell apoptosis in the kidney illustrations after APAP overdose and (C) inhibition of APAP-induced acute kidney injury by 4MP but not NAC.