Table 3.
The results of the BALB/c mice infection experiment.
Strains | Mortality rate (%)a | CC | Deaths at different post-infection time points | Total deaths | Mortality rate (%)b | P value | Significancec | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 d | 2 d | 3 d | 4 d | 5 d | 6 d | 7 d | 8 d | 9 d | 10 d | |||||||
WUSS406 | 80.00 | 17 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 100.00 | 0.3173 | ns |
2018WUSS011 | 93.33 | 17 | 5 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 8 | 80.00 | 0.0111 | * |
ND84 | 86.67 | 17 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 60.00 | 0.0317 | * |
ND90 | 80.00 | 17 | 7 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 80.00 | 0.1512 | ns |
ID36054 | 93.33 | 94 | 9 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 100.00 | >0.9999 | ns |
2021WUSS075 | 93.33 | 94 | 9 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 100.00 | >0.9999 | ns |
2018WUSS156 | 86.67 | 94 | 6 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 80.00 | 0.0863 | ns |
WUSS346 | 93.33 | 839 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 100.00 | 0.3173 | ns |
2018WUSS160 | 100.00 | 839 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 90.00 | 0.5567 | ns |
2022WUSS018 | 0.00 | / | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | <0.0001 | **** |
2022WUSS056 | 0.00 | / | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | <0.0001 | **** |
SC070731 | 93.33 | 1 | 9 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 100.00 | - | - |
PBS | 0.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | <0.0001 | **** |
Mortality rate of each strain in zebrafish.
Mortality rate of each strain in BALB/c mice.
The survival outcome of serotype 4 strains for mice was compared with that of the highly pathogenic strain SC070731 using the Log-rank (Mantel-Cox) test. * indicates p < 0.05, ** indicates p < 0.01, *** indicates p < 0.001, **** indicates p < 0.0001, and “ns” indicates no significant difference.
/: unassigned.