Table 2.
Migraine-Related Characteristics/Outcomes and Clinical Characteristics by MiRS Group (n = 59,001),a as a Percentage of All Respondents
| MiRS group | Minimizing burden/secondary gain/both often/very often (N = 18,708; 31.7%) | SMD Minimizing burden/secondary gain/both often/very often vs never |
||||||
| Never (N = 6,715; 11.4%) | Rarely/sometimes (N = 33,578; 56.9%) | Minimizing burden Often/very often (N = 9,987; 16.9%) |
Secondary gain Often/very often (N = 1,556; 2.6%) |
Both often/very often (N = 7,165; 12.1%) | Total (N = 59,001) | |||
| Migraine-related characteristics/outcomes | ||||||||
| Monthly headache days, n (%)b | ||||||||
| 0–3 | 4,807 (71.6) | 21,112 (62.9) | 4,779 (47.9) | 914 (58.7) | 3,164 (44.2) | 34,776 (58.9) | 8,857 (47.3) | 0.51 |
| 4–7 | 966 (14.4) | 6,363 (18.9) | 2,312 (23.2) | 327 (21.0) | 1,592 (22.2) | 11,560 (19.6) | 4,231 (22.6) | 0.21 |
| 8–14 | 479 (7.1) | 3,218 (9.6) | 1,400 (14.0) | 164 (10.5) | 1,022 (14.3) | 6,283 (10.6) | 2,586 (13.8) | 0.22 |
| 15+ | 463 (6.9) | 2,885 (8.6) | 1,496 (15.0) | 151 (9.7) | 1,387 (19.4) | 6,382 (10.8) | 3,034 (16.2) | 0.29 |
| MIDAS, n (%)b | ||||||||
| Little or no disability (score = 0–5) | 4,703 (70.0) | 14,819 (44.1) | 2,241 (22.4) | 307 (19.7) | 848 (11.8) | 22,918 (38.8) | 3,396 (18.2) | 1.23 |
| Mild disability (score = 6–10) | 767 (11.4) | 6,201 (18.5) | 1,714 (17.2) | 248 (15.9) | 950 (13.3) | 9,880 (16.7) | 2,912 (15.6) | 0.12 |
| Moderate disability (score = 11–20) | 582 (8.7) | 5,794 (17.3) | 2,213 (22.2) | 376 (24.2) | 1,545 (21.6) | 10,510 (17.8) | 4,134 (22.1) | 0.38 |
| Severe disability (score = 21+) | 663 (9.9) | 6,764 (20.1) | 3,819 (38.2) | 625 (40.2) | 3,822 (53.3) | 15,693 (26.6) | 8,266 (44.2) | 0.84 |
| MIBS-4, n (%)b | ||||||||
| No interictal burden (score = 0) | 4,224 (62.9) | 10,998 (32.8) | 1,839 (18.4) | 69 (4.4) | 339 (4.7) | 17,469 (29.6) | 2,247 (12.0) | 1.24 |
| Mild interictal burden (score = 1–2) | 1,088 (16.2) | 6,481 (19.3) | 1,736 (17.4) | 88 (5.7) | 409 (5.7) | 9,802 (16.6) | 2,233 (11.9) | 0.12 |
| Moderate interictal burden (score = 3–4) | 648 (9.6) | 5,328 (15.9) | 1,804 (18.1) | 119 (7.6) | 707 (9.9) | 8,606 (14.6) | 2,630 (14.1) | 0.14 |
| Severe interictal burden (score = 5+) | 755 (11.2) | 10,771 (32.1) | 4,608 (46.1) | 1,280 (82.3) | 5,710 (79.7) | 23,124 (39.2) | 11,598 (62.0) | 1.24 |
| MSQ-RFR, mean (SD) | 68.7 (24.5) | 58.0 (21.8) | 45.5 (21.7) | 43.2 (18.8) | 34.8 (20.2) | 53.9 (23.9) | 41.2 (21.5) | 1.20 |
| Clinical characteristics | ||||||||
| BMI group, n (%)b | ||||||||
| Underweight/normal | 2,284 (34.0) | 11,699 (34.8) | 3,400 (34.0) | 600 (38.6) | 2,524 (35.2) | 20,507 (34.8) | 6,524 (34.9) | 0.02 |
| Overweight | 1,859 (27.7) | 9,115 (27.1) | 2,564 (25.7) | 374 (24.0) | 1,740 (24.3) | 15,652 (26.5) | 4,678 (25.0) | 0.06 |
| Obese | 2,141 (31.9) | 11,118 (33.1) | 3,642 (36.5) | 481 (30.9) | 2,549 (35.6) | 19,931 (33.8) | 6,672 (35.7) | 0.08 |
| No answer | 431 (6.4) | 1,646 (4.9) | 381 (3.8) | 101 (6.5) | 352 (4.9) | 2,911 (4.9) | 834 (4.5) | 0.09 |
| Total comorbidities, mean (SD)b | 3.0 (2.7) | 3.6 (2.9) | 4.2 (3.1) | 4.6 (3.6) | 5.1 (3.4) | 3.8 (3.1) | 4.6 (3.3) | 0.52 |
| PHQ-4, mean (SD)b | 2.6 (3.1) | 3.9 (3.2) | 5.4 (3.4) | 6.1 (3.1) | 7.0 (3.3) | 4.5 (3.5) | 6.1 (3.4) | 1.00 |
Abbreviations: BMI = body mass index; MIDAS = Migraine Disability Assessment; MIBS-4 = Migraine Interictal Burden Scale-4; MiRS = Migraine-Related Stigma; MSQ-RFR = Migraine Specific Quality of Life v2.1 Role Function-Restrictive; SMD = standardized mean difference.
Minimizing burden/secondary gain/both often/very often column reflects the mean (SD) or percentage when combining the individual columns of minimizing burden often/very often, secondary gain often/very often, and both often/very often.
a
See eTable 2 (links.lww.com/WNL/D342) for full variable description.
b
All comparisons were significant p < 0.001.