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Kaplan-Meier curves of adverse events among the groups of complete closure and left atrial appendage (LAA) patency with and without visible peri-device leak (PDL). Kaplan-Meier curves of ischemic stroke or transient ischemic attack (TIA; A), major bleeding (B), cardiovascular (CV) death (C), all-cause death (D), and major adverse events (MAEs; E). For multiple comparisons, the Bonferroni corrected critical P value was set as 0.05/3 to 0.017.
