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. 2024 May 2;18:1379933. doi: 10.3389/fnins.2024.1379933

Table 1.

Age, gendersex, initial symptoms, primary symptoms, CSF testing, MRI, and mRS scores of patients with anti-DPPX encephalitis.

Characteristics N (%)
Sex
Male
Female

9/14 64.3%
5/14 35.7%
Age, year
Mean (range)

45.93 (11–72)
Initial symptoms
Gastrointestinal symptoms
Dizziness
Ataxia
Seizures
Cognitive impairment
Fever
Hallucinations
Headache

5/14 35.7%
4/14 28.6%
3/14 21.4%
2/14 14.3%
2/14 14.3%
2/14 14.3%
2/14 14.3%
1/14 7.1%
Primary symptoms
Cognitive impairment
CNS hyperexcitability
Myoclonus
Seizures
Limb convulsions
Gastrointestinal symptoms
Psychiatric abnormalities
Hallucinations
Dizziness
Ataxia
Weight loss
Consciousness changes
Nystagmus
Sleep disturbances
Bulbar dysfunction
Weakness in lower limbs

7/14 50.0%
6/14 42.9%
3/6
2/6
1/6
5/14 35.7%
5/14 35.7%
4/14 28.6%
4/14 28.6%
3/14 21.4%
2/14 14.3%
2/14 14.3%
2/14 14.3%
2/14 14.3%
1/14 7.1%
1/14 7.1%
CSF testing
Normal
Protein >500 mg/L
Chloride >130 mmol/L
Glucose >4.5 mmol/L
Pleocytosis

9/14 64.3%
2/14 14.3%
2/14 14.3%
1/14 7.1%
0/14 0.0%
MRI
Normal or nonspecific changes
Atrophy or swollen in the hippocampus
Cerebellar atrophy
Frontotemporal abnormal signals

8/14 57.1%
3/14 21.4%
2/14 14.3%
1/14 7.1%
mRS at admission
2
3
4
5

1/14 7.1%
6/14 42.9%
5/14 35.7%
2/14 14.3%
mRS at discharge
0
1
2
4

1/14 7.1%
7/14 50.0%
5/14 35.7%
1/14 7.1%
mRS at follow-up
0
1
2
5

4/14 28.6%
5/14 35.7%
2/14 14.3%
3/14 21.4%

CSF, cerebrospinal fluid; MRI, magnetic resonance imaging; mRS, modified Rankin Scale; CNS, central nervous system.