Table 3. Meta-analysis of the correlation coefficient between PLR level and SLIDAI, C3, C4, ESR, CRP, proteinuria, and anti-dsDNA in SLE.
| Parameters | No. of studies | Test of association | Test of heterogeneity | ||||
|---|---|---|---|---|---|---|---|
| Correlation coefficient | 95% CI | p-value | Model | p-value | I2 | ||
| SLEDAI | 12 | 0.325 | 0.176–0.459 | < 0.001 | R | < 0.001 | 87.8 |
| ESR | 9 | 0.252 | 0.076–0.412 | 0.005 | R | < 0.001 | 86.5 |
| CRP | 8 | 0.215 | 0.119–0.307 | < 0.001 | R | 0.040 | 52.2 |
| C3 | 5 | -0.280 | -0.356- -0.200 | < 0.001 | F | 0.405 | 0.260 |
| C4 | 5 | -0.181 | -0.352–0.002 | 0.052 | R | 0.001 | 77.4 |
| Proteinuria | 4 | 0.298 | 0.088–0.483 | 0.006 | R | 0.005 | 75.8 |
| Anti-dsDNA | 1 | 0.325 | 0.137–0.490 | 0.001 | NA | NA | NA |
PLR: Platelet to lymphocyte ratio, SLEDAI: Systemic lupus erythematosus disease activity index, ESR: Erythrocyte sedimentation rate, CRP: C-reactive protein, CI: Confidence interval, R: Random effects model, NA: Not available.