Table 3.

Patients meeting SLICC classification criteria only (N=138).

REASONS FOR NOT MEETING ACR CRITERIA:	Number	Example
3 criteria only	N= 85
Low complement - not part of ACR:	N= 17	e.g. ANA, [low complement], arthritis, oral ulcers
Alopecia - not part of ACR:	N= 21	e.g. ANA, [alopecia], arthritis, lymphopenia
Unique NP criteria not part of ACR:	N= 13	e.g. ANA, anti-dsDNA antibody, [transverse myelitis], lymphopenia
Unique cutaneous criteria not part of ACR:	N= 2	e.g. ANA, anti-dsDNA antibody, photosensitive rash, [Chillblains lupus]
Overlapping hematologic criteria:	N=6	e.g. ANA, seizures, [lymphopenia, thrombocytopenia]
Lymphopenia not met by ACR:	N= 2	e.g. ANA, APL, arthritis, [lymphopenia – NON-ACR]
Direct Coombs’ test (DAT) in the absence of hemolytic anemia:	N=3	e.g. ANA, anti-dsDNA antibody, leukopenia, +DAT
Combinations of above:	N=21	e.g. ANA, anti-Smith antibody, oral ulcers, [alopecia], [peripheral neuropathy]
≤ 2 criteria only:	N= 53
ANA, Renal:	N=1	e.g. ANA, Class V
2 or more described above for ≤ 3 criteria:	N= 52	e.g. ANA, arthritis, [alopecia, peripheral neuropathy]
REASONS FOR NOT MEETING EULAR/ACR CRITERIA:
ANA negative:	N=25
Sufficient points to meet EULAR/ACR if ANA positive:	N=21 [range 10-21, mean 13.95]	e.g. anti-dsDNA antibody, alopecia, leukopenia, thrombocytopenia
Insufficient points to meet EULAR/ACR if ANA positive:	N=4 [range 7-9, mean 8]	e.g. low complement, oral ulcer, [neuropathy], leukopenia, thrombocytopenia
ANA <1:80, not sufficient for entry:	N=17
Sufficient points to meet EULAR/ACR if ANA titer met entry criteria :	N=4 [range 10–12, mean 10.75]	e.g. ANA (1:40), anti-Smith antibody, alopecia, leukopenia, [lymphopenia], thrombocytopenia
Insufficient points to meet EULAR/ACR if ANA titer was sufficient:	N=13 [range 0–9, mean 6.7]
Overlapping criteria within same domain:	N=5	e.g. ANA (1:40), malar, discoid, alopecia
At least one unique SLICC criterion:	N=6	e.g. ANA (1:40), [photosensitivity], [neuropathy], [lymphopenia]
Overlapping criteria/Unique SLICC criteria:	N=1	e.g. ANA (1:40), [neuropathy], leukopenia, thrombocytopenia
< 10 points:	N=1	e.g. ANA (1:40), low C3, leukopenia, alopecia
ANA positive/sufficient titer for entry, not meeting points threshold > 10:	N=95 [range 2–9, mean 6.9]
Overlapping criteria:	N=18	e.g. ANA, discoid, leukopenia, thrombocytopenia
At least one unique SLICC criteria:	N=54	e.g. ANA, low C3, [panniculitis], alopecia, leukopenia, [lymphopenia]
Overlapping criteria/Unique criteria:	N=12	e.g. ANA, anti-Smith antibody, oral ulcers, alopecia, [peripheral neuropathy]
< 10 points:	N=11	e.g. ANA, Renal Class V
ANA positive/sufficient points, but immunologic criteria only:	N=1	e.g. ANA, anti-dsDNA antibody, low complements, [RBC casts]

Abbreviations: ACR-American College of Rheumatology, EULAR- European Alliance of Associations for Rheumatology, SLICC- Systemic Lupus International Collaborating Clinics, ANA-antinuclear antibody, NP-Neuropsychiatric, aPL = antiphospholipid antibody, RBC = red blood cell

Bolded font in Examples column: overlapping criteria falling within the same domain, [Brackets]: criteria not part of, or does not meet, the specified classification criteria