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. Author manuscript; available in PMC: 2024 May 16.
Published in final edited form as: Acad Radiol. 2023 Sep 2;31(3):1148–1159. doi: 10.1016/j.acra.2023.08.003

Table 3:

Change in Whole-Lung PRM and Pulmonary Function Measurements

Subtypes
FT FD ED P-Value
Parametric Response Map [%]
 Norm −8.4 (14.6) −5.2 (10) −4.3 (8.3) 0.027
 fSAD 9 (13.7) 5.7 (8.9) 1.4 (7.8) <0.0001
 Emph 1.2 (2.4) 1.8 (3.2) 3.8 (4.9) <0.0001
 PD −1.6 (7.8) −1.9 (5.1) −0.7 (3.7) <0.0001
Pulmonary Function [mL/yr]
 FEV1 −45.2 (61.2) −50.7 (60.6) −47.7 (58.5) 0.101
 FVC −45.6 (84.7) −62.1 (85.1) −67.9 (104) 0.014
 FEF25–75 −54.9 (116.5) −36.1 (98.1) −23.3 (68.1) <0.0001

Note: Change in whole-lung PRM and pulmonary function measurements separated by subsets of those designated fSAD-transition (FT), fSAD-dominant (FD) and emphysema-dominant (ED). Values are displayed as mean (standard deviation). Norm, Normal; fSAD, functional small airways disease; Emph, emphysema; PD, parenchymal disease; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; FEF25–75, forced expiratory flow at 25–75% of FVC.