Table 4.

Tyr/Thr was associated with the presence of HF in all subjects

	Unadjusted OR	P value	Adjusted OR	P value
HF (n = 318)
Tyr/Thr tertiles	3.225 (2.307–4.507)	<0.001	3.928 (2.649–5.825)	<0.001
Tertile 1	1 (ref)		1 (ref)
Tertile 2	3.603 (2.096–6.192)	<0.001	4.856 (2.567–9.185)	<0.001
Tertile 3	9.721 (4.826–19.584)	<0.001	14.020 (6.332–31.043)	<0.001
HF with DCM (n = 131)
Tyr/Thr tertiles	3.696 (2.500–5.463)	<0.001	3.491 (1.752–6.953)	<0.001
Tertile 1	1 (ref)		1 (ref)
Tertile 2	4.287 (2.208–8.322)	<0.001	2.966 (0.993–8.857)	0.051
Tertile 3	12.997 (5.902–28.618)	<0.001	13.186 (3.013–57.708)	0.001
HF with IHD (n = 187)
Tyr/Thr tertiles	2.912 (2.042–4.154)	<0.001	3.826 (2.349–6.232)	<0.001
Tertile 1	1 (ref)		1 (ref)
Tertile 2	3.247 (1.808–5.832)	<0.001	7.327 (3.171–16.928)	<0.001
Tertile 3	8.018 (3.840–16.741)	<0.001	11.686 (4.514–30.252)	<0.001

The presence risk of HF (n = 318), HF with DCM (n = 131), or HF with IHD (n = 187) was analysed in combination with controls (n = 100), respectively. Adjusted for sex, age, BMI, low systolic BP, heart rate, smoking, drinking, DM, hyperlipidaemia, stroke, AF, coronary disease, ALT, and low eGFR.

DCM, dilated cardiomyopathy; HF, heart failure; IHD, ischaemic heart disease; OR, odds ratio.