Figure 1.

(A) Scatter plots demonstrating the correlation of age with TDD of CIV divided by body weight (mg/kg/day) and (C) body surface area (mg/m²/day) in courses that achieved a therapeutic steady-state concentration. Linear regression lines (solid blue) have been fitted to the data points. (B) Boxplots comparing the TDD of CIV divided by body weight (mg/kg/day) and (D) body surface area (mg/m²/day) between two age-based cohorts in courses that achieved a therapeutic steady-state concentration. The top and bottom of the boxplots show the 25^th and 75^th percentile and the dark band shows the median. The dots represent outliers. CIV = continuous infusion vancomycin; TDD = total daily dose