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. 2024 May 16;17:225. doi: 10.1186/s13071-024-06306-5

Table 2.

Molecular diversity indices from the combined β-tubulin genotype dataset stratified by host and country

Molecular diversity indices
Group Molecular diversity Hardy-Weinberg equilibrium Population-specific FIS indices (1023 permutations)
Sample size No. of haplotypes Average gene diversity over loci Locus Obs. Het Exp. Het P-value FIS P(Rand FIS ≥ Obs FIS)
HBG 22 7 0.433 A 0.273 0.455 0.232 0.412 0.226
B 0.364 0.411 0.451
HET 58 7 0.305 A 0.069 0.131 0.105 0.477 0.111
B 0.483 0.479 0.671
HTZ 184 22 0.626 A 0.250 0.526  < 0.001a 0.526  < 0.001a
B 0.696 0.726 0.375
HUG 16 4 0.421 A 0.500 0.500 1  < 0.001a 0.778
B 0.375 0.342 1
PBM 208 32 0.652 A 0.269 0.456  < 0.001a 0.411  < 0.001a
B 0.750 0.847 0.044a
PDK 14 9 0.632 A 0.286 0.440 0.440 0.368 0.436
B 0.714 0.824 0.195
PHG 26 11 0.712 A 0.385 0.588 0.048a 0.355 0.096a
B 0.385 0.837 0.000a
PPH 10 4 0.367 A N/A N/A N/A N/A N/A
B 0.200 0.733 0.016a
PTZ 16 6 0.571 A 0.500 0.500 1  < 0.001a 0.789
B 0.125 0.642 0.001a
PUG 16 9 0.675 A 0.375 0.575 0.439 0.364 0.182
B 0.625 0.775 0.168
PUK 46 11 0.552 A 0.304 0.486 0.014a 0.379 0.025a
B 0.478 0.617 0.107
Farm A 32 6 0.353 A 0.063 0.179 0.032a 0.659 0.029a
B 0.563 0.526 0.580
Farm B 36 3 0.282 A 0.889 0.508 0.002a -0.167 1
B 0.056 0.056 1
Farm C 34 11 0.528 A 0.412 0.355 1 0.252 0.163
B 0.294 0.701  < 0.001a
Farm D 28 9 0.566 A 0.286 0.378 0.316 -0.789 1
B 0.357 0.754 0.001a

aIndicates a p-value < 0.05. Abbreviations: Obs.Het. = observed heterozygosity, Exp.Het. = expected heterozygosity, H = humans, P = pig, BG = Bangladesh, BM = Belgium, DK = Denmark, ET = Ethiopia, GT = Guatemala, HG = Hungary, NP = Nepal, PH = Philippines, TZ = Tanzania, UG = Uganda, UK = United Kingdom. Farms A, B, C and D indicate the separate pig farms from the UK. Hardy-Weinberg equilibrium is calculated for each isotype over 1,000,000 Markov chain steps, and the p-value is based on the deviation between the observed and expected values. Population-specific inbreeding coefficient (FIS) calculated over 1023 permutations is shown for each population with p-values of divergence between random FIS vs observed FIS