Table 2.
Molecular diversity indices | |||||||||
---|---|---|---|---|---|---|---|---|---|
Group | Molecular diversity | Hardy-Weinberg equilibrium | Population-specific FIS indices (1023 permutations) | ||||||
Sample size | No. of haplotypes | Average gene diversity over loci | Locus | Obs. Het | Exp. Het | P-value | FIS | P(Rand FIS ≥ Obs FIS) | |
HBG | 22 | 7 | 0.433 | A | 0.273 | 0.455 | 0.232 | 0.412 | 0.226 |
B | 0.364 | 0.411 | 0.451 | ||||||
HET | 58 | 7 | 0.305 | A | 0.069 | 0.131 | 0.105 | 0.477 | 0.111 |
B | 0.483 | 0.479 | 0.671 | ||||||
HTZ | 184 | 22 | 0.626 | A | 0.250 | 0.526 | < 0.001a | 0.526 | < 0.001a |
B | 0.696 | 0.726 | 0.375 | ||||||
HUG | 16 | 4 | 0.421 | A | 0.500 | 0.500 | 1 | < 0.001a | 0.778 |
B | 0.375 | 0.342 | 1 | ||||||
PBM | 208 | 32 | 0.652 | A | 0.269 | 0.456 | < 0.001a | 0.411 | < 0.001a |
B | 0.750 | 0.847 | 0.044a | ||||||
PDK | 14 | 9 | 0.632 | A | 0.286 | 0.440 | 0.440 | 0.368 | 0.436 |
B | 0.714 | 0.824 | 0.195 | ||||||
PHG | 26 | 11 | 0.712 | A | 0.385 | 0.588 | 0.048a | 0.355 | 0.096a |
B | 0.385 | 0.837 | 0.000a | ||||||
PPH | 10 | 4 | 0.367 | A | N/A | N/A | N/A | N/A | N/A |
B | 0.200 | 0.733 | 0.016a | ||||||
PTZ | 16 | 6 | 0.571 | A | 0.500 | 0.500 | 1 | < 0.001a | 0.789 |
B | 0.125 | 0.642 | 0.001a | ||||||
PUG | 16 | 9 | 0.675 | A | 0.375 | 0.575 | 0.439 | 0.364 | 0.182 |
B | 0.625 | 0.775 | 0.168 | ||||||
PUK | 46 | 11 | 0.552 | A | 0.304 | 0.486 | 0.014a | 0.379 | 0.025a |
B | 0.478 | 0.617 | 0.107 | ||||||
Farm A | 32 | 6 | 0.353 | A | 0.063 | 0.179 | 0.032a | 0.659 | 0.029a |
B | 0.563 | 0.526 | 0.580 | ||||||
Farm B | 36 | 3 | 0.282 | A | 0.889 | 0.508 | 0.002a | -0.167 | 1 |
B | 0.056 | 0.056 | 1 | ||||||
Farm C | 34 | 11 | 0.528 | A | 0.412 | 0.355 | 1 | 0.252 | 0.163 |
B | 0.294 | 0.701 | < 0.001a | ||||||
Farm D | 28 | 9 | 0.566 | A | 0.286 | 0.378 | 0.316 | -0.789 | 1 |
B | 0.357 | 0.754 | 0.001a |
aIndicates a p-value < 0.05. Abbreviations: Obs.Het. = observed heterozygosity, Exp.Het. = expected heterozygosity, H = humans, P = pig, BG = Bangladesh, BM = Belgium, DK = Denmark, ET = Ethiopia, GT = Guatemala, HG = Hungary, NP = Nepal, PH = Philippines, TZ = Tanzania, UG = Uganda, UK = United Kingdom. Farms A, B, C and D indicate the separate pig farms from the UK. Hardy-Weinberg equilibrium is calculated for each isotype over 1,000,000 Markov chain steps, and the p-value is based on the deviation between the observed and expected values. Population-specific inbreeding coefficient (FIS) calculated over 1023 permutations is shown for each population with p-values of divergence between random FIS vs observed FIS