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. 2024 Apr 10;26(5):784–796. doi: 10.1038/s41556-024-01401-2

Fig. 4. Transcription-coupled removal of histone-DPC.

Fig. 4

a, Schematic representation of the experimental procedure for histone-DPC-seq in cultured cells. b,c, Metagene profile from histone-DPC-seq within or near transcribed regions of genes with TPM ≥ 30 (b) and 0.1 ≤ TPM < 1 (c) at 0 and 4 h after formaldehyde washout in WT and ΔCSB HeLa cells. Data represent the average of three replicates. d, Histone-DPC residual ratios in WT or ΔCSB HeLa cells, shown in seven gene-length bins with TPM ≥ 100. Means (±s.e.m.) from three independent experiments are shown. Two-sided unpaired t-test. Source numerical data are available in the source data.