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. 2024 Apr 8;13(5):965–990. doi: 10.1007/s40121-024-00952-z

Table 8.

Median values of the highest quality studies of human papillomavirus (HPV) transmission, recovery, reactivation, and waning parameters

Parameter Median value (low, high)a References
Probability of HPV breakthrough transmission from men to vaccinated women per partnership/contact 0.5450 (0.2800, 0.8100) Lee et al. [80]
Probability of HPV breakthrough transmission from women to vaccinated men per partnership/contact 0.1200 (0.0500, 0.1900) Lee et al. [80]
Probability of HPV transmission from men to women per partnership/contact 0.0700 (0.0600, 0.0700) Nyitray et al. [81]
Probability of HPV transmission from women to men per partnership/contact 0.1600 (0.1400, 0.1800) Nyitray et al. [81]
Proportion of HPV infections that become persistent 5.6000 (0.1000, 42.3000) Insinga et al. [38]
Rate of recovery from HPV infection 0.4856 (0.3685, 0.8064) Insinga et al. [38]
Rate of seroconversion following HPV clearance 2.8972 (1.6434, 4.1431) Reisinger et al. [82]
Rate of waning immunity following recovery for persons who seroconvert 0.0240 (0.0150, 0.0470) Johnson et al. [83]
Reactivation rate following seroconversion 0.0075 (0.0000, 0.3100) Joura et al. [84]
Relative rate of recovery from breakthrough infection 1.3117 (1.0523, 1.5211) Zhao et al. [85]
Transmission rate of HPV from men to women 0.0876 (0.0504, 0.0912) Nyitray et al. [81]
Transmission rate of HPV from women to men 0.1476 (0.1128, 0.1620) Nyitray et al. [81]

HPV human papillomavirus

aRates are in units of 1/years