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. 2024 May 16;7:577. doi: 10.1038/s42003-024-06283-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Representative collagen zymography gel loaded with the secretomes of CUS and CAS fibroblasts. M molecular weight (kDa) of standard proteins. b Densitometric analysis of all bands from CUS and CAS fibroblasts. The boxplots show the median (center line), interquartile range (bounds of box), the range of typical data values (whiskers). Data represent means ± SD of measures from three independent experiments performed in triplicate on cell lines kept separate (n = 3 biological replicates for CUS and n = 3 biological replicates for CAS). *p < 0.05.