Figure 1.

Manhattan plots for three fear-related behaviors in mice

(A–C) The data show the results of a meta-analysis of (A) 1,931 mice for cue conditioning (FC-cue), (B) 2,671 for contextual conditioning (FC-context), and (C) 1,942 for entries into the open arms of the elevated plus maze (EPM-open arms). Chromosome numbers are listed on the horizontal axis. The vertical scale is the negative logarithm (base 10) of the association p value. A horizontal dotted red line gives the location of the 5% significance threshold (from simulation).