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. 2024 May 15;16(5):1869–1877. doi: 10.4251/wjgo.v16.i5.1869

Table 2.

Univariate and multivariate analyses for overall survival in the training cohort

Variables Univariate analysis
P value
Multivariate analysis
P value
HR (95%CI)
HR (95%CI)
Gender Male 1 - - -
Female 5.755 (0.660, 50.196) 0.033 - -
Age ≥ 75 1.745 (0.198, 15.416) 0.064 - -
< 75 1 - - -
Obstruction Yes 0.785 (0.035, 17.665) 0.014 - -
No 1 - - -
CEA (ng/mL) > 5 1.576 (0.497, 4.994) 0.434 - -
≤ 5 1 - - -
CA199 (U/mL) > 37 20.20 (1.881, 216.893) 0.002 6.315 (1.520, 26.243) 0.011
≤ 37 1 - 1 -
Surgical procedure Laparotomy 1.586 (0.130, 19.331) 0.012 - -
Laparoscopy 1 - - -
Right hemicolon Yes 2.873 (0.775, 10.656) 0.016 5.236 (1.229, 22.308) 0.025
No 1 - 1 -
Enterostomy Yes 6.086 (1.949, 19.007) 0.000 13.302 (3.392, 52.171) 0.000
No 1 - 1 -
Tumor size (cm) ≥ 6.8 2.252 (0.376, 13.489) 0.004 - -
< 6.8 1 - - -
Poor differentiated Yes 4.311 (1.341, 13.856) 0.008 - -
No 1 - - -
T stage T4a 1 - 1 -
T4b 8.241 (2.500, 27.158) 0.000 10.888 (2.809, 42.199) 0.001
Lymph node count ≥ 12 1 - - -
< 12 1.143 (0.250, 5.225) 0.863 - -
Regular review Yes 1 - 1 -
No 5.676 (1.534, 21.000) 0.003 4.626 (1.075, 19.905) 0.040

CEA: Carcinoembryonic antigen; CA199: Carbohydrate antigen 199.