Table 1.
Risk factors |
Univariable Cox regression
|
Multivariable Cox regression
|
||
HR (95%CI)
|
P value
|
HR (95%CI)
|
P value
|
|
Age as per 1 yr increase | 1.088 (1.039-1.140) | < 0.001 | 1.067 (1.015-1.121) | 0.011 |
Diastolic blood pressure as per 1 mmHg increase | 0.954 (0.917-0.993) | 0.020 | 0.935 (0.887-0.985) | 0.011 |
Hemoglobin as per 1 g/L increase | 0.980 (0.965-0.995) | 0.011 | ||
Troponin I > 0.028 as per 1 μg/L increase | 6.377 (2.841-14.311) | 0.001 | 6.576 (2.586-16.727) | < 0.001 |
Carcinoembryonic antigen as per 1 ng/mL increase | 1.009 (1.005-1.013) | < 0.001 | 1.009 (1.004-1.015) | < 0.001 |
Carbohydrate antigen 125 as per 1 ng/mL increase | 1.015 (1.004-1.026) | 0.008 | ||
LVPW as per 1 mm increase | 1.375 (1.112-1.701) | 0.003 | ||
LDL-C as per 1 mmol/L increase | 0.570 (0.328-0.989) | 0.046 | ||
Tumor stage, TNM 3-4 vs 1-2 | 3.211 (1.329-7.762) | 0.010 | ||
Radical operation history as yes vs no | 0.295 (0.100-0.868) | 0.027 | ||
Lee score ≥ 2 as yes vs no | 6.201 (1.424-27.003) | 0.015 | ||
Premature ventricular contractions > 35 as yes vs no | 2.764 (1.181-6.468) | 0.019 | ||
NSVT as yes vs no | 1.836 (0.547-6.163) | 0.326 |
CI: Confidence interval; HR: Hazard ratio; LDL-C: Low density lipoprotein cholesterol; LVPW: Left ventricular posterior wall; NSVT: Non-sustained ventricular tachycardia; TNM: Tumor, node, metastasis.