Table 3. Population specific minor allele frequencies for C4A and C4B unphased, non-synonymous exonic sequence variants.

For this analysis we did not distinguish between C4A and C4B. This table shows amino acid frequencies, the amino acid position and nucleotide position, the nucleotide frequencies, and population allele frequencies for the minor allele. Major amino acids and nucleotides represent the most frequent global variant while minor amino acids and nucleotides represent the second most frequent variant. This data was filtered to only show variants with allele frequencies >= 2% for any population. Blank values represent absence of the variant. See Table 1 for population abbreviations.

	aa pos	141	229	325	328	478	549	726	791	916	959	1286	1413	1530
	major aa	L	T	K	M	P	H	P	R	R	E	A	A	P
	minor aa	V	I	M	I	L	P	L	H	Q	D	S	P	S
	nuc pos	E3 157	E6 60	E9 62	E9 72	E12 92	E13 122	E17 106	E18 103	E21 155	E23 23	E29 180	E33 6	E36 4
	major nuc	C	C	A	G	C	A	C	G	G	A	G	G	C
	minor nuc	G	T	T	A	T	C	T	A	A	C	T	C	T
EUR	GBR	6.1					2.6					7.8
	FIN	8.4					5.9				2.2	4.5
	IBS	3.2					2.1					4.6
	CEU	6.1					5.5					8.2
	TSI	4.1					4.1					3.8
EAS	CHS	35.8					14.3				8.6	3.6
	CDX	53.3					18.7				17.7
	KHV	33.7	2.1	4.4	4		10.2				13
	CHB	25.8		2.9	2.9		12.8				4.6	5.6
	JPT	13.3		4.4	4.2		8					13.1
AMR	PUR	8.7					3					3.1
	CLM	7.7					3.9					2.4
	PEL	16					6.8				2.7
	MXL	15.8					7					2.2
SAS	PJL	4					4					5.7
	BEB	16.1					3.8				7.4	4.8
	STU	8					4					4.6
	ITU	8.8					5.5				2.9	6.4
	GIH	6.3					3.1					5.9
AFR	ACB	7				3.5			2.2				2.2	2.2
	GWD	5.1				3.8				3.1	2.3		4.5
	ESN	10.6				4.7					2.3
	MSL	3.5								4.3			10.2	10.2
	YRI	10.5				4.1					2.4		4	4
	LWK	10.7						3.1		2.1			2.9	3.7
	ASW	10.7					2.5						2.1	2.8