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. 2000 Oct;182(19):5530–5538. doi: 10.1128/jb.182.19.5530-5538.2000

FIG. 8.

FIG. 8

Model for acquisition of ctxAB by the two V. cholerae O1 biotypes. An ancestral V. cholerae isolate gave rise to the classical and El Tor biotypes, which were subsequently independently infected with divergent CTXφs. CTXφ probably arose from a precursor CTXφ that acquired the CT genes by imprecise excision from a unknown donor strain.