TABLE 3.
N | BILT (mg/dL) | HGB (gr/dL) | URI (mg/dL) | CREA (mg/dL) | GOT (U/L) | GPT (U/L) | ALP (U/L) | GGT (U/L) | |
---|---|---|---|---|---|---|---|---|---|
Sex | |||||||||
Men | 414 | 0.72 (0.35) | 15.10 (1.02) | 5.38 (1.01) | 0.90 (0.12) | 21.95 (9.42) | 20.78 (10.77) | 70.94 (19.39) | 19.47 (13.66) |
Women | 359 | 0.58 (0.28)* | 12.86 (1.01)* | 3.95 (0.91)* | 0.70 (0.11)* | 18.68 (6.75)* | 15.04 (6.40)* | 63.76 (18.76)* | 14.63 (8.50)* |
Biogeographical origin | |||||||||
European | 434 | 0.65 (0.32) | 14.15 (1.47) | 4.81 (1.22) | 0.82 (0.15) | 20.24 (8.24) | 17.67 (8.07) | 63.44 (18.23) | 15.07 (9.88) |
Latin-American | 330 | 0.65 (0.34) | 13.94 (1.56) | 4.58 (1.15)*1 | 0.79 (0.16)*1 | 20.36 (8.27) | 18.51 (10.88) | 73.06 (19.54)*1 | 20.04 (13.52)*1 |
Other# | 9 | 0.63 (0.36) | 14.26 (1.53) | 5.29 (1.50) | 0.87 (0.20) | 32.22 (15.01)*2 | 24.78 (12.56) | 68.44 (23.28) | 17.22 (6.16) |
UGT1A1 phenotype | |||||||||
NM | 357 | 0.56 (0.23) | 14.14 (1.56) | 4.88 (1.23) | 0.81 (0.15) | 20.39 (8.56) | 18.04 (9.21) | 66.64 (20.15) | 17.62 (13.62) |
IM | 318 | 0.64 (0.27)*3 | 14.09 (1.47) | 4.65 (1.12) | 0.81 (0.16) | 20.63 (7.94) | 18.30 (8.24) | 68.64 (18.47) | 16.98 (10.58) |
PM | 98 | 1.03 (0.49)*3 | 13.64 (1.42)*4 | 4.32 (1.20)*5 | 0.79 (0.14) | 19.95 (9.58) | 17.73 (13.32) | 67.74 (19.78) | 16.54 (7.68) |
Data are shown as mean (standard deviation) although these are non-parametric tests following the central limit theorem. BILT: total bilirubin. HGB: hemoglobin. URI: uric acid. CREA: creatinine. GOT: glutamic oxaloacetic transaminase. GPT: glutamic pyruvic transaminase. ALP: alkaline phosphatase. GGT: gamma glutamyl transpeptidase. # Other: American, Near Eastern, East Asian and Sub-Saharan African.* univariate p-value (p uv) < 0.05 compared to men. *1 p uv<0.05 compared to European. *2 p uv<0.05 compared to European and p uv<0.05 compared to Latin-American. *3 p uv<0.05 compared to NM. *4 p uv<0.05 compared to NM, and IM. *5 p uv<0.05 compared to NM.,
p uv<0.05 compared to NM., underlined: multivariate p-value (p mv) < 0.5.