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. 2024 May 16;23:150. doi: 10.1186/s12936-024-04981-4

Table 2.

Prevalence of key drug resistance mutations

Mutation Prevalence proportion Confidence interval (95% CI)
K13
 R561H 0.235 (20/85) 0.150–0.340
 A675V 0.064 (6/94) 0.024–0.134
 P574L 0.024 (2/84) 0.003–0.083
 F699C 0.011 (1/87) 0.000–0.062
 R575K 0.011(1/88) 0.000–0.062
DHPS
 A437G 0.878 (72/82) 0.787–0.940
 K540E 0.784 (69/88) 0.684–0.865
 A581G 0.427 (38/89) 0.323–0.536
 A613S 0.034 (3/87) 0.007–0.98
 S436A 0.000 (0/82) 0.000–0.044*
 A613T 0.000 (0/87) 0.000–0.042*
DHFR
 S108N 1.000 (80/80) 0.955–1.000*
 N51I 0.934 (85/91) 0.862–0.975
 C59R 0.922 (83/90) 0.846–0.968
 I164L 0.247 (19/77) 0.156–0.358
MDR1
 N86Y 0.955 (84/88) 0.888–0.988
 Y184F 0.717 (66/92) 0.614–0.806
 D1246Y 0.979 (95/97) 0.928–0.998
 N1042D 0.054 (5/93) 0.18–0.121
CRT
 K76T 0.0610 (5/82) 0.20–0.137

*One sided 97.5% CI