Table 3.

Clinical trials on phytochemicals/phytoconstituents employed in the management of NDs

S.No.	Phytoconstituents	Mechanism of action	NCT number	Sponsor	Status
1	Ginkgo biloba	Antioxidant activity and anti-amyloid aggregation	NCT03090516	Nanjing Medical University	Recruiting
2	Guanfacine	Alpha-2A-adrenoceptor agonist, an effective 5-HT2B receptor agonist	NCT03116126	Imperial College London	Recruiting
3	Coconut oil	Attenuation in the expression of ADP-ribosylation factor-1 protein	NCT01883648	University of South Florida	Terminated
4	Caffeine	Antagonizes the adenosine receptors and improves the motor system and also has an impact on Levodopa serum concentrations	NCT01738178	Research Institute of the McGill University Health Centre	Recruitment- Completed
5	Huperzine-A	Cholinesterase inhibitor, also decreases the levels of soluble and insoluble beta-amylase levels in AD	NCT00083590	-	Recruitment- Completed