Table 1.
Number of female and male participants surveyed for lifetime use of illicit substance and substance use disorders and result for Chi-Sqaure test of association between prevalence and sex.
| Females | Males | Assoc: prevalence and sex (DF=1) | ||||
|---|---|---|---|---|---|---|
|
|
||||||
| Target phenotype | N (%) | Cases (%) | N (%) | Cases (%) | χ2 | p-value |
|
| ||||||
| Ever used cocaine | 1336 (58%) | 184 (14%) | 976 (42%) | 238 (24%) | 41.86 | < .0001 |
| Ever used amphetamine | 1335 (58%) | 235 (18%) | 975 (42%) | 223 (23%) | 9.51 | 0.0020 |
| Ever used inhalants | 1331 (58%) | 45 (3%) | 972 (42%) | 72 (7%) | 18.06 | < .0001 |
| Ever used sedatives | 1334 (58%) | 177 (13%) | 975 (42%) | 153 (16%) | 2.51 | 0.1133 |
| Ever used hallucinogens | 1334 (58%) | 139 (10%) | 974 (42%) | 201 (21%) | 45.97 | < .0001 |
| Ever used opioids | 1335 (58%) | 72 (5%) | 974 (42%) | 64 (7%) | 1.20 | 0.2725 |
| Ever used ecstasy | 1337 (58%) | 318 (24%) | 975 (42%) | 333 (34%) | 29.46 | < .0001 |
| Ever used prescription pain killers | 1335 (58%) | 246 (18%) | 974 (42%) | 179 (18%) | 0.00 | 1.0000 |
| Ever used prescription stimulants | 1334 (58%) | 151 (11%) | 973 (42%) | 162 (17%) | 13.18 | 0.0003 |
| Ever used cannabis | 1106 (59%) | 450 (41%) | 784 (41%) | 443 (57%) | 45.42 | < .0001 |
| Alcohol abuse | 1368 (59%) | 386 (28%) | 959 (41%) | 390 (41%) | 38.76 | < .0001 |
| Alcohol dependence | 1368 (59%) | 305 (22%) | 959 (41%) | 343 (36%) | 50.25 | < .0001 |
| DSM-5 AUD (ctrl mild vs moderate severe) | 1368 (59%) | 310 (23%) | 959 (41%) | 352 (37%) | 53.94 | < .0001 |
| Cannabis abuse | 1368 (59%) | 105 (8%) | 959 (41%) | 165 (17%) | 49.00 | < .0001 |
| Cannabis dependence | 1368 (59%) | 61 (4%) | 959 (41%) | 91 (9%) | 22.55 | < .0001 |
| DSM-5 CUD (ctrl mild vs moderate severe) | 1368 (59%) | 75 (5%) | 959 (41%) | 122 (13%) | 37.20 | < .0001 |