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. 2024 May 13;19(1):47. doi: 10.5334/gh.1327

Table 2.

The WHF 2012 criteria for the echocardiographic diagnosis of RHD.


A) 2012 WHF guidelines for diagnosis of RHD

Definite RHD (either A, B, C or D):
A. Pathological MR and at least two morphological features of RHD of the MV
B. MS mean gradient ≥4 mmHg
C. Pathological AR and at least two morphological features of RHD of the AV
D. Borderline disease of both the AV and MV
Borderline RHD (either A, B, or C)
A. At least two morphological features of RHD of the MV without pathological MR or MS
B. Pathological MR
C. Pathological AR

B) Criteria for pathological regurgitation

Pathological mitral regurgitation (All four Doppler echocardiographic criteria must be met)
  • Seen in two views.

  • In at least one view, jet length ≥2 cm

  • Velocity ≥3 m/s for one complete envelope

  • Pan-systolic jet in at least one envelope

Pathological aortic regurgitation (All four Doppler echocardiographic criteria must be met)

  • See in two views.

  • In at least one view, jet length ≥1 cm

  • Velocity ≥3 m/s in early diastole

  • Pan-diastolic jet in at least one envelope


C) Morphological features of RHD

Features in the MV
  • AMVL thickening ≥3 mm (age-specific)

  • Chordal thickening

  • Restricted leaflet motion

  • Excessive leaflet tip motion during systole

Features in the AV

  • Irregular of focal thickening

  • Coaptation defect

  • Restricted leaflet motion

  • Prolapse


WHF: World Heart Federation; RHD: Rheumatic Heart Disease; MR: Mitral Regurgitation; MV: Mitral Valve; AR: Aortic Regurgitation; AV: Aortic Valve; MS: Mitral Stenosis; AMVL: Anterior Mitral Valve Leaflet