|
Diagnostic Feature(s) |
Diamantino et al. [29] |
Beaton et al. [21] |
Lu et al. [28] |
Remenyi et al. [30] |
Zuhlke et al. [24] |
|
Modified protocol |
PLAX with colour Doppler. |
11 image protocol (same as STAND) |
11 image protocol, excluded CW |
PLAX with sweep of the heart and color Doppler |
PLAX with color Doppler |
|
Modified criteria |
Valve regurgitation only |
CW replaced with regurgitation jet seen in ≥2 consecutive frames |
Assessed multiple parameters that maximised sensitivity and specificity |
Valve regurgitation or morphological features |
|
|
Definition of screen positive |
MR ≥1.5 cm, any AR |
N/A |
MR ≥1.5 cm or any AR found to have the best compromise |
Any MR or AR seen in 2 consecutive frames, ≥2 morph features of MV |
MR ≥2 cm |
|
Diagnosis of RHD |
As per WHF |
As per WHF |
As per WHF |
As per WHF |
As per WHF |
|
Sensitivity c/f ref WHF criteria by standard echocardiography for any RHD |
81.10% |
78.9%% |
73.30% |
100% |
80.80% |
|
Specificity c/f ref WHF criteria by standard echocardiography for any RHD |
75.50% |
87.2%% |
82.40% |
95% |
100% |
|
PPV & NPV for any RHD |
63.2%; 88.5% |
|
|
44%; 100% |
100%, 92.5% |
|