Table 2:

Large Publicly Available Cell Painting Datasets covering Compound or Genetic Perturbations

Dataset	Release Date	Type of Perturbations	Cell Line	Number of unique perturbations (compounds or genetic)	References
Bray et al. Cell Painting Dataset	January 2017	Compounds	U20S	30,616 bioactive compounds	50
Recursion RxRx3 dataset	January 2023	CRISPR/Cas9-mediated gene knockouts and compounds with dose-response	HUVEC	17,063 CRISPR/Cas9-mediated gene knockouts (most anonymized) and 1,674 compounds at 8 concentrations each	51
JUMP-CP dataset	March 2023	Over-expression of genes, knockout of genes using CRISPR-Cas9, and compounds	U20S	Over-expression of 12,602 genes, knockout of 7,975 genes using CRISPR-Cas9,116,750 unique compounds	22