Extended Data Fig. 5 |. Deuterium labeling of cholesterol, as well as long-chain (myristic) and very-long-chain (ximenic) fatty acids upon treatment with GSK2194069 Fasnall in BT-474 cells grown in 20% D2O medium.

a, Cholesterol deuterium isotopologue distribution. b-c, Total deuterium labeling (b) and the isotopologue distribution (c) for myristic acid. d-e, Total deuterium labeling (d) and the isotopologue distribution (e) for ximenic acid. Data are mean ± SD, n = 3.