Figure 4. Long-lived postmitotic fly tissues decommission enhancers at select, rate-limiting cell cycle genes.

ATAC-Seq accessibility data at e2f1 (A), cycE (B) and stg (C) gene loci across tissues and time points. Arrows on gene diagrams indicate the direction of transcription. Y-axes indicate the normalized read counts per million. Boxes highlight example regions of shared accessibility across two or more tissues. Red arrows highlight example regions of tissue-specific accessibility.