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Effects of daily REL-1017 s.c. chronic treatment on body weight. The graphs show body weights of the wild type (gray line), and of G93A SOD1 mice, starting from day 45 (beginning of REL-1017 treatment) for female (A) and male (B) mice. Data are shown as mean ± SEM for each time point. Onset of 10%-body weight loss in female (C) and male (D) G93A SOD1 mice. **p < 0.01 vs. vehicle, ###p < 0.001 vs. mice treated with REL-1017 3 mg/kg.
