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Effect of REL-1017 on survival of G93A SOD1 mice. Lifespan (A for females, C for males) and Kaplan–Meier survival curves (B for females, D for males) of G93A SOD1 mice. ***p < 0.001 vs. vehicle, ###p < 0.001 vs. mice treated with REL-1017 3 mg/kg. In (D) ****p < 0.0001 vs. vehicle and REL-1017 3 mg/kg.
