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Effect of REL-1017 treatment on mRNA (A,C) and protein (B,D) of GluN1 subunit in muscle of G93A SOD1 mice. Data are presented as mean ± S.E.M. *p < 0.05 vs. vehicle-treated mice (n = 3 mice per group). Representative images of the immunoreactive bands are reported in panels B and D. V, vehicle; 5, REL-1017 5 mg/kg; 10, REL-1017 10 mg/kg; 3, REL-1017 3 mg/kg; 6, REL-1017 6 mg/kg.
