Remodeling Kinetics	Enzyme	K	95% CI
	WT	3.2pM/s	2.6 to 3.8
	LLD	0.58pM/s	0.39 to 0.78
	DBD	0.72pM/s	0.52 to 0.94
	R3	ND	ND
	△516–564	ND	ND
ATPase kinetics table	WT	1.3nM/s	0.93 to 1.7
	LLD	0.52nM/s	0.29 to 0.75
	DBD	0.78nM/s	0.61 to 0.94
	R3	0.27nM/s	0.14 to 0.40
	△516–564	0.34nM/s	0.31 to 0.38
Site directed Mapping kinetics	Type of Movement	Enzyme	K	95% CI	Plateau	95% CI
Fig. 7A&E	32 bp exit side	WT	0.014nM/s	0.011 to 0.018	52.78	50.38 to 55.23
	32 bp exit side	mut LLD	0.0049nM/s	0.0034 to 0.0070	42.8	38.38 to 47.48
	32 bp exit side	mut DBD	0.0022nM/s	0.0012 to 0.0044	26.74	20.76 to 33.93
	33 bp exit side	mut R3	0.0022nM/s	0.0010 to 0.0049	17.62	14.12 to 22.32
Fig. 7B&F	20bp entry side	WT	0.098nM/s	0.056 to 0.19	12.2	10.52 to 13.97
	20bp entry side	mut LLD	0.021nM/s	0.0084 to 0.048	3.416	2.787 to 4.079
	20bp entry side	mut DBD	0.018nM/s	0.0095 to 0.034	4.204	3.617 to 4.814
	20bp entry side	mut R3	0.0019nM/s	0.0011 to 0.0031	2.509	2.157 to 2.975
Fig. 7C	Loss / Initial position-entry	WT	0.010nM/s	0.0036 to 0.021	---	---
	Loss / Initial position-entry	mut LLD	0.0066nM/s	---	---	---
	Loss / Initial position-entry	mut DBD	0.012nM/s	0.0011 to 0.044	---	---
Fig. 3F& 7D	Net loss - entry	WT	0.0053nM/s	0.0032 to 0.0081
	Net loss - entry	mut LLD	0.0015nM/s	---
	Net loss - entry	mut DBD	0.0048nM/s	0.00011 to 0.017
	Net loss - entry	mut R3	---	---