Fig 2. Comparative analysis of the degree of association of ALT and ALT/AST ratio with IR indices in Korean men.

The association between the liver enzyme profile and IR index was calculated using four linear regression models, including different combinations of covariates. Model 1 was a univariate model with the liver enzyme profile and IR indices as the dependent and independent variables, respectively. Model 2 included age as the covariate. Model 3 included age, DM, dyslipidemia, and alcohol consumption as confounders. Model 4 included age, DM, dyslipidemia, alcohol consumption, BMI, and WC as confounding factors. Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; HTN, hypertension; DM, diabetes mellitus; BMI, body mass index; WC, waist circumference; Glc, fasting blood glucose; HOMA-IR, Homeostasis model assessment for insulin resistance; HOMA-β, HOMA for β cell.