Figure 4.

Evaluating the performance of signature genes within GSE30122. (a, b) Boxplots illustrating expression levels of signature genes in DKD tubulointerstitial injury and healthy cohort. (c, d) ROC curve analysis of the diagnostic performance of signature genes CASP1 and LYZ. (e, f) Expression levels of CASP1 and LYZ in tubulointerstitial injury patients versus healthy controls based on the Nephroseq v5 dataset. (g, h) Correlations between CASP1/LYZ expression and GFR in tubulointerstitial injury patients compared to healthy controls using the Nephroseq v5 dataset.