Table 1.

Demographic and Drug Dosing Characteristics

	Midazolam/hydromorphone (n = 92)	Midazolam/meperidine (n = 65)	P valuea
Age, mean (SD), y	4.02 (0.8)	4.03 (0.7)	.94
Gender, n (%)			.62
Male	39 (42.4)	31 (47.7)
Female	53 (57.6)	34 (52.3)
Weight, mean (SD), kg	17.1 (1.7)	17.0 (1.8)	.72
Midazolam dosing
Total dose, mean (SD), mg	16.7 (2.1)	15.5 (2.6)	.002b
Weight-based dose, mean (SD), mg/kg	0.98 (0.07)	0.91 (0.11)	<.001b
Hydromorphone dosing
Total dose, mean (SD), mg	0.5 (0.1)	—	n/a
Weight-based dose, mean (SD), mg/kg	0.03 (0.004)	—	n/a
Meperidine dosing
Total dose, mean (SD), mg	—	23.8 (6.2)	n/a
Weight-based dose, mean (SD), mg/kg	—	1.4 (0.3)	n/a

^aChi-square or Fisher exact test, unless otherwise indicated.

^bP < .05.