Table 1.
Summary of patient and tumor characteristics in the total population and by subgroup
| Total population | Lymph node negative | Lymph node positive | Age ≤ 50 years (premenopausal) | Age ≥ 60 years (postmenopausal) | |
|---|---|---|---|---|---|
| Median age (IQR), years | 56 (49–63) | 57 (50–64) | 53 (47–61) | 45 (41–48) | 65 (62–68) |
| Median tumor size (IQR), cm | 1.6 (1.2–2.2) | 1.4 (1.1–1.9) | 2.1 (1.5–2.7) | 1.8 (1.4–2.5) | 1.5 (1.1–2.0) |
| Tumor type, n (%) | |||||
| Ductal (including mixed) | 681 (85.02) | 464 (84.67) | 217 (85.77) | 215 (87.40) | 247 (82.61) |
| Lobular | 83 (10.36) | 54 (9.85) | 29 (11.46) | 22 (8.94) | 38 (12.71) |
| Mixed no special type and lobular | 1 (0.12) | 1 (0.18) | 0 (0.00) | 0 (0.00) | 1 (0.33) |
| Special type | 35 (4.37) | 29 (5.29) | 6 (2.37) | 8 (3.25) | 13 (4.35) |
| Tubular | 1 (0.12) | 0 (0.00) | 1 (0.40) | 1 (0.41) | 0 (0.00) |
| Tumor grade, n (%) | |||||
| 1 | 168 (20.97) | 134 (24.45) | 34 (13.44) | 34 (13.82) | 75 (25.08) |
| 2 | 395 (49.31) | 267 (48.72) | 128 (50.59) | 106 (43.09) | 148 (49.50) |
| 3 | 238 (29.71) | 147 (26.82) | 91 (35.97) | 106 (43.09) | 76 (25.42) |
| Lymph node status, n (%) | |||||
| Negative | 548 (68.41) | 548 (100.00) | 0 (0.00) | 148 (60.16) | 226 (75.59) |
| 1–3 positive | 253 (31.59) | 0 (0.00) | 253 (100.00) | 98 (39.84) | 73 (24.41) |
| Pleomorphism, n (%) | |||||
| 1 | 17 (2.12) | 14 (2.55) | 3 (1.19) | 3 (1.22) | 9 (3.01) |
| 2 | 300 (37.45) | 219 (39.96) | 81 (32.02) | 63 (25.61) | 131 (43.81) |
| 3 | 477 (59.55) | 309 (56.39) | 168 (66.40) | 176 (71.54) | 157 (52.51) |
| Missing data | 7 (0.87) | 6 (1.09) | 1 (0.40) | 4 (1.63) | 2 (0.67) |
| Nottingham prognostic index, n (%) | |||||
| Good prognostic score | 371 (46.32) | 346 (63.14) | 25 (9.88) | 79 (32.11) | 159 (53.18) |
| Moderate prognostic score | 371 (46.32) | 202 (36.86) | 169 (66.80) | 138 (56.10) | 125 (41.81) |
| Poor prognostic score | 58 (7.24) | 0 (0.00) | 58 (22.92) | 28 (11.38) | 15 (5.02) |
| Missing data | 1 (0.12) | 0 (0.00) | 1 (0.40) | 1 (0.41) | 0 (0.00) |
| Recurrence | |||||
| No | 642 (80.15) | 459 (83.76) | 183 (72.33) | 190 (77.24) | 240 (80.27) |
| Yes | 159 (19.85) | 89 (16.24) | 70 (27.67) | 56 (22.76) | 59 (19.73) |