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. 2024 May 17;14:11302. doi: 10.1038/s41598-024-61956-w

Table 1.

The univariate and multivariate analyses assessing the relation between clinical, radiological, laboratory features and F2-IsoP levels regarding DCI occurrence.

Total n = 27 DCI n = 13 (48.1%) Without DCI n = 14 (51.9%) Univariate OR (95% CI) P value Multivariate OR (95% CI) P value
Age (years) 61 (50–66) 63 (61–70) 54 (43–61) 1.05 (0.99–1.12) 0.099
Sex (male) 11 (41%) 6 (46%) 5 (36%) 1.53 (0.32–7.22) 0.582
Location (anterior circulation) 24 (89%) 13 (100%) 11 (79%) N.A 1.000
Treatment (surgical treatment) 24 (89%) 13 (100%) 11 (79%) N.A 1.000
Hunt and Hess scale
 I 1 (4%) 0 (0%) 1 (7.1%) 1.73 (0.47–6.4) 0.405
 II 8 (30%) 3 (23%) 5 (35.8%)
 III 17 (63%) 10 (77%) 7 (50%)
 IV 1 (4%) 0 (0%) 1 (7.1%)
mFisher grade
 I 3 (11%) 0 (0%) 3 (21.5%) 3.57 (1.14–11.13) 0.028
 II 4 (15%) 0 (0%) 4 (28.5%)
 III 4 (15%) 3 (23%) 1 (7.2%)
 IV 16 (59%) 10 (77%) 6 (42.8%)
Intracerebral haemorrhage (ICH) 5 (18.5%) 2 (15.4%) 3 (21.4%) 0.66 (0.09–4.8) 0.687
Hydrocephalus (HCP) 14 (51.8%) 8 (61.5%) 6 (42.8%) 2.13 (0.45–9.94) 0.334
Anisocytosis parameters
 RDW-CV (%CV)—day 1 13.8 ± 1.5 13 (12–15) 14.5 ± 1.8 14 (13–15) 13.2 ± 0.9 13(12–13) 1.92 (1.02–3.61) 0.042 1.289 (1.041–1.597) 0.020
 RDW-SD (fl)—day 1 43.5 ± 8.9 42 (39–50) 47.2 ± 10 49 (44–53) 40.1 ± 6 40 (38–42) 1.11 (1–1.23) 0.049
 RDW-CV (%CV)—day 3 12.5 ± 0.8 12 (11–13) 12.6 ± 0.9 12 (11–13) 12.4 ± 0.8 12 (11–12) 1.32 (0.55–3.16) 0.525
 RDW-SD (fl)—day 3 42.1 ± 4.5 42 (39–44) 41.6 ± 6 40 (38–44) 42.5 ± 2.5 43(40–44) 0.95 (0.8–1.13) 0.581
 RDW-CV (%CV)—day 5 12.9 ± 0.9 12 (12–13) 12.8 ± 1 12 (11–13) 12.9 ± 0.8 13 (12–13) 0.84 (0.36–1.94) 0.690
 RDW-SD (fl)—day 5 41.7 ± 4 40 (39–44) 41.5 ± 4 40 (38–43) 41.9 ± 3.6 42 (39–44) 0.97 (0.8–1.17) 0.774
ISOP CSF conc
 Day 1 (pg/ml) 43.9 ± 42 25 (16–67) 65.7 ± 50 67 (23–83) 23.7 ± 19 20 (7–28) 1.04 (1–1.08) 0.028 1.094 (1.005–1.191) 0.039
 Day 3 (pg/ml) 49.3 ± 37 43 (16–80) 65.8 ± 39 76 (21–94) 36.4 ± 30 22 (12–59) 1 (0.98–1) 0.878
 Day 5 (pg/ml) 46 ± 32 43 (22–53) 61.7 ± 52 (43–76) 31.4 ± 17 34 (16–43) 1.05 (1.004–1.097) 0.031