Adjusted associations between (a) normalized ALP and (b) normalized PTH and time-to-event clinical outcomes. Cox models stratified by DOPPS phase and country, adjusted for demographics: age, sex, Black race, dialysis vintage, 13 comorbid conditions, single pool Kt/V, body mass index, serum albumin, serum creatinine, hemoglobin. Adjusted hazard ratio of PTH <1 for hip fracture was 0.52 (95% confidence interval: 0.33–0.83). ALP, alkaline phosphatase; DOPPS, Dialysis Outcomes and Practice Patterns Study; PTH, parathyroid hormone.