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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Br J Haematol. 2023 Oct;203(1):65–78. doi: 10.1111/bjh.19078

Figure 6.

Figure 6.

Schematic representation of the mechanism(s) of action of anti-CD38 monoclonal antibodies on plasma cells. NK cell, natural killer cell; ADCC, antibody-dependent cell-medicated cytotoxicity; CDC, complement-mediated cytotoxicity; ADCP, antibody-dependent cellular phagocytosis; cADPR, cyclic adenosine diphosphate ribose; NAD+, nicotinamide adenine dinucleotide. Adapted from Morandi et al (33)., originally published in Frontiers in Immunology (copyright owner Frontiers Media S.A.) as per the Creative Commons Attribution License (CC BY).