Fig. 3.

Profiles of NK receptors on NK cells from dengue infected patients

Scattered plots of frequencies of NK cells expressing indicated NK receptors in DF and DHF patients are demonstrated. Expression of individual NK receptors were determined in activated NK cells (CD56⁺CD3⁻CD69⁺) in acute samples and in non-activated NK cells (CD56⁺CD3⁻CD69⁻) in convalescent samples. (A) Natural cytotoxic receptors (NCRs): NKp30 (left), NKp44 (middle) and NKp46 (right). (B) Lectin-like receptors (NKG2- family): NKG2A (left), NKG2C (middle) and NKG2D (right). (C) Killer immunoglobin-like receptors (KIRs): KIR2DL1/S1 (left), KIR2DL2/L3/S2 (middle) and KIR3DL1/S1 (right). Horizontal bars indicate means, and the error bars indicate standard deviation (SD). Differences between acute and convalescent samples were determined using Wilcoxon signed rank test. Differences between DF and DHF samples were determined using Mann-Whitney U test. Asterisks indicate P-values: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. “ns.” indicates a non-statistically significant.