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. 2024 Apr 15;14(2):90–105. doi: 10.62347/NSWR6869

Figure 3.

Figure 3

Time courses of changes in cardiac functional characteristics in WT and S14A mice. A-E. LV echocardiographic functional parameters from the same cohort of mice used for Figure 2 are presented. The stacked line chart of each panel summarizes the time course of changes in the indicated parameter. The detailed values of echocardiographic parameters are listed and statistical significance between genotypes or sexes at the same time point are presented in Tables 1, 2, 3, 4, 5 and 6. The bar graph with scattered dots of each panel presents the area under curve (AUC) of the indicated parameter versus time obtained with the trapezoidal rule. Each dot represents an individual mouse; Mean ± SD; repeated three-way ANOVA followed by Tukey’s test for the time-course curves, and two-way ANOVA followed by Sidak’s test for AUC; EF, ejection fraction; FS, fractional shortening; SV, stroke volume; CO, cardiac output per minute; HR, heart rate; ns, not significant.