Fig. 2.

i Bubble plots compare photo-ageing as evaluated through studying wrinkle variations. Evaluations conducted by our three trained assessors are compared with the self-reported evaluation by the participant. For the evaluation performed by our assessors, the phenotype is determined to be present only if all three assessors identify it to be present. Larger circles indicate greater concordance between the two scales. Numbers in the circles are the number of concordances. The sample size of each plot is 1081 participants. ii Bubble plots compare photo-ageing as evaluated through studying dyspigmentation patterns. Evaluations conducted by our three trained assessors are compared with the self-reported evaluation by the participant. For the evaluation performed by our assessors, the phenotype is determined to be present only if all three assessors identify it to be present. Larger circles indicate greater concordance between the two scales. Numbers in the circles are the number of concordances. The sample size of each plot is 1081 participants