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. 2024 May 18;16:112. doi: 10.1186/s13195-024-01477-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Serum NfL, plasma NTA-tau and plasma t-tau concentrations in cognitively unimpaired APOE ε4 homozygotes (ε4ε4), heterozygotes (ε4ε3) and noncarriers (ε3ε3). Raw concentrations, median, first and third quartile and range are presented by the box plot, p values are further adjusted for age and sex. P-values below the figures presents overall difference between groups