Table 3.

Investigation on proposed thresholds for leukocyte count and relative neutrophils percentage

Author (reference)	Population	Proposed cutoff	Sensitivity	Specificity
Kusuma SK [44]	76 knee spacers	1102 cells/µL 71% PMN	75% 75%	61% 66%
Hoell et al. 2016 [46]	115 spacers (56 hips and 59 knees)	970 cells/µL NA	31% NA	39% NA
Newman et al. 2017 [41]	77 hip spacers	3000 cells/µL 80% PMN	47% 76%	87% 80%
Zmistowski et al. 2017 [42]	128 spacers (40 hips and 88 knees)	1234 cells/µL 57% PMN	44% 67%	77% 59%
Boelch et al. 2018 [45]	94 knee spacers	4450 cells/uL NA	50% NA	76% NA
Ascione et al. 2021 [43]	82 knee spacers	934 cells/µL 52%	82% 82%	82% 78%

NA not available, PMN polymorphonuclear leukocyte