Table 1.

Expression of ethanol-nicotine withdrawal signs in different experimental groups.

Experimental group	Number of animals displaying withdrawal signs (out of 10)
	Tremor	Eye blink	Yawning	Grooming
Vehicle	0	0	0	0
Nic-Eth	10****	9 ***	10****	8***
Nic-Eth-CoQ10 (100mg/kg)	10	9 ***	9 ***	9 ***
Nic-Eth-CoQ10 (200mg/kg)	6 *	7 **	7 **	6 *
Nic-Eth-CoQ10 (400mg/kg)	5 *	4	5 *	6 *
Nic-Eth-Bup-Nal	4	5 *	5 *	5 *
CoQ10 400mg/kg	0	0	0	0

*vs. Vehicle, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, Data analyzed by Fisher's exact test, n = 10 in each group.