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. 2024 May 18;24:578. doi: 10.1186/s12903-024-04365-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Time-resolved changes in the microbial load and diversity of supragingival plaque in subjects with moderate gingivitis after twice daily brushing followed by rinsing with a mouthrinse for 30 s. Box plots of the total microbial load A, Shannon-Weaver diversity index B, and observed species richness C are shown. Error bars represent the range of values. *p < 0.05, **p < 0.01, ***p < 0.001 (mixed model repeated measures with baseline covariate and terms for treatment, visit, treatment-by-visit and baseline-by-visit, and unstructured within-subject covariance). ACPM alcohol-containing prototype mouthrinse, AFPM alcohol-free prototype mouthrinse, LCM Listerine® COOL MINT