Table 1.
Subject demographic and baseline characteristics
| Parameters | Healthy (n = 32) | HA (n = 31) | LCM (n = 31) | ACPM (n = 29) | AFPM (n = 30) | Overall p-value |
|---|---|---|---|---|---|---|
| Mean age (range), years | 45.9 (25 − 66) | 41.9 (20 − 64) | 42.1 (22 − 72) | 41.1 (20 − 69) | 44.5 (18 − 70) | 0.591a |
| Sex, n (%) | ||||||
| Male | 8 (25.0) | 8 (25.8) | 7 (22.6) | 8 (27.6) | 8 (26.7) | 0.994b |
| Female | 24 (75.0) | 23 (74.2) | 24 (77.4) | 21 (72.4) | 22 (73.3) | |
| Body mass index (range) | 26.8 (17.3 − 40.9) | 30.1 (20.4 − 64.1) | 30.8 (21.0 − 42.0) | 31.4 (20.1 − 55.7) | 29.7 (21.9 − 39.9) | 0.101a |
| Race, n (%) | ||||||
| White | 27 (84.4) | 29 (93.5) | 29 (93.5) | 26 (89.7) | 26 (86.7) | 0.724c |
| Black or African American | 5 (15.6) | 2 (6.5) | 2 (6.5) | 3 (10.3) | 4 (13.3) | |
| Smoker, n (%) | ||||||
| No | 32 (100.0) | 31 (100.0) | 31 (100.0) | 29 (100.0) | 30 (100.0) | 0.997b |
| Whole-mouth scores ± SD | ||||||
| Baseline mean MGI | 0.438 ± 0.115 | 2.510 ± 0.289 | 2.614 ± 0.242 | 2.578 ± 0.221 | 2.416 ± 0.223 | < 0.001a |
| Baseline mean TPI | 2.530 ± 0.392 | 2.984 ± 0.434 | 3.111 ± 0.356 | 3.009 ± 0.380 | 2.898 ± 0.417 | < 0.001a |
| Baseline mean EBI | 0.018 ± 0.013 | 0.339 ± 0.171 | 0.378 ± 0.192 | 0.356 ± 0.153 | 0.348 ± 0.241 | < 0.001a |
ap-values are based on an ANOVA model with term for treatment
bp-values are based on Chi-square test
cp-values are based on Fisher’s exact test
ACPM alcohol-containing prototype mouthrinse, AFPM alcohol-free prototype mouthrinse, HA hydroalcohol negative control, LCM LISTERINE COOL MINT Antiseptic mouthrinse